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ATLANTA: 1800 Howell Mill Rd • Suite 800 • Atlanta, GA 30318 • 404-350-9853
FAYETTEVILLE: 1267 Highway 54 West • Suite 4200 • Fayetteville, GA 30214 • 678-829-1060
LOCUST GROVE: 4877 Bill Gardner Pkwy • Locust Grove, GA 30248 • 678-399-7190
NEWNAN: 775 Poplar Rd. • Suite 310 • Newnan, GA 30265 • 770-251-2590
SANDY SPRINGS: 755 Mount Vernon Hwy NE • Suite 320 • Atlanta, GA 30328 • 404-350-8711
STOCKBRIDGE: 290 Country Club Drive • Suite 100 • Stockbridge, GA 30281 • 678-854-9500

Meet Samantha Shams, MD

Dr. Samantha Shams joined Piedmont Cancer Institute following her fellowship at the Moffitt Cancer Center at the University of South Florida.

Dr. Shams' passion for medical sciences, research, and education culminated in a prestigious grant in affiliation with the Harvard Macy Medical Educators Program.

Today, Dr. Shams' focus is on translating her medical knowledge to give patients cutting-edge cancer treatments, while never losing sight of the whole patient. She treats patients with all cancer types given her experience in oncology and hematology.

Dr. Shams' personal interests include cooking, yoga, travel and spending time with family and friends.

Professional Affiliations

Testimonials from Dr. Shams' Patients

June 2026

Dr. Samantha Shams is an absolute rockstar. From day one, she has made an incredibly scary and overwhelming cancer diagnosis and process feel manageable. She is not only exceptionally smart and knowledgeable, but also deeply compassionate and genuinely caring. She checks in frequently, stays on top of every detail, and always makes me feel heard and supported. Her attention to detail, expertise, and kindness have given me tremendous confidence throughout my treatment. I truly cannot say enough good things about her. If you are looking for an oncologist who combines brilliance with compassion, I highly recommend Dr. Shams. I am beyond grateful to have her leading my care.

June 2026

Dr. Shams is extremely knowledgeable. She keeps me informed and follows through with what she says. I always feel confident I'm in good hands!

June 2026

Dr. Shams is always caring and thorough in my son's examination and asks me if we have any concerns. I feel that my son is being treated with the utmost care and compassion.

June 2026

Dr Shams is an excellent doctor! At each appointment she provides comprehensive care and there is always an opportunity to ask any question. Her staff is efficient and kind. I am very thankful for her care!!

May 2026

Dr. Shams is experienced and knowledgeable, but more importantly she is empathetic, responsive, and excellent at explaining complex medical issues. Everyone in her office, from front desk staff (especially Jessica), phlebotomists, and PAs are kind, helpful, and excellent at what they do. I recommend Dr. Shams, and her staff, very highly.

May 2026

Dr.Samantha Shams and entire staff are wonderful , knowledgeable , patient , caring . Take time to explains the test results and answer any questions . From the PA , nurses to the lab technicians they all are absolutely the best.

April 2026

Dr Shams is an incredibly smart doctor and an even better human. She is compassionate when I needed it and inspiring throughout my treatment. I very much recommend Dr Shams.

April 2026

Dr Shams is a gem! She has my highest recommendation.

April 2026

Dr. Shams is an outstanding physician who exudes warmth and caring while still being professional. I have the utmost confidence in her knowledge and expertise.

February 2026

Update: we now have visits at the Mt. Vernon, Sandy Springs location. Jessica is amazing, as is Sarah, and all staff... so very kind and helpful! Dr. Shams is the best! I highly recommend this practice - they are all so very kind to my 95 yr old client. Thank you all for your help in caring for her. Dr. Shams takes her time to explain and makes the complete process as easy as possible for my 93 year old client. Dr. Shams' scheduler is amazing. She takes pride in helping ...she actually cares !!!

January 2026

Dr. Shams is a star on many accounts. The best way I can explain our relationship is that she is like the sister I never had. Our conversations are very frank, built with mutual trust over 30 years of being a patient. She is very knowledgeable and relatable. I always look forward to my appointments because they are always positive and I feel like I have some control over my treatment.

January 2026

Dr. Shams is professional, knowledgeable, and has good bedside manner. She is tagged with an incredible team that is thorough and punctual. I appreciated the time she took to review my charts from my hospital stay, info received from her PA, and answered all of my questions. I visited her Sandy Springs office which was easy to find and had a minimal wait to be seen (which is a huge plus for me). Front office staff is very courteous!

December 2025

The staff is always very friendly, kind and efficient. I never have to wait more than a few minutes to be taken back for bloodwork, etc.

December 2025

Dr. Shams is an excellent Doctor. Took time to hear my problems and concerns.

December 2025

Dr Shams is fabulous; very caring and sensitive.

View Testimonials About PCI

Office Locations

Samantha Shams, MD sees patients at the following PCI offices.

The Atlanta office of Piedmont Cancer Institute | Atlanta Oncologists

Atlanta

1800 Howell Mill Rd, Suite 800, Atlanta, GA 30318

404-350-9853

Map & Directions

The Sandy Springs office of Piedmont Cancer Institute | Atlanta Oncologists

Sandy Springs

755 Mount Vernon Hwy NE, Suite 320, Atlanta, GA 30328

404-350-8711

Map & Directions

Seven Atlanta Area Locations

Providing the highest quality cancer treatment services close to home.

WebMD Preferred Provider Castle Connolly Top Physician Practices GASCO Lifetime Group Member Georgia Trend Top Doctors Atlanta Magazine Top Doctors 2024 Atlanta Magazine Top Doctors 2023 Best of Perimeter 2023 Best of North Atlanta 2025 Best of North Atlanta 2024 Atlanta's Best 2023 Kev's Best