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ATLANTA: 1800 Howell Mill Rd • Suite 800 • Atlanta, GA 30318 • 404-350-9853
FAYETTEVILLE: 1267 Highway 54 West • Suite 4200 • Fayetteville, GA 30214 • 678-829-1060
LOCUST GROVE: 4877 Bill Gardner Pkwy • Locust Grove, GA 30248 • 678-399-7190
NEWNAN: 775 Poplar Rd. • Suite 310 • Newnan, GA 30265 • 770-251-2590
SANDY SPRINGS: 755 Mount Vernon Hwy NE • Suite 320 • Atlanta, GA 30328 • 404-350-8711
STOCKBRIDGE: 290 Country Club Drive • Suite 100 • Stockbridge, GA 30281 • 678-854-9500

Meet Samantha Shams, MD

Dr. Samantha Shams joined Piedmont Cancer Institute following her fellowship at the Moffitt Cancer Center at the University of South Florida.

Dr. Shams' passion for medical sciences, research, and education culminated in a prestigious grant in affiliation with the Harvard Macy Medical Educators Program.

Today, Dr. Shams' focus is on translating her medical knowledge to give patients cutting-edge cancer treatments, while never losing sight of the whole patient. She treats patients with all cancer types given her experience in oncology and hematology.

Dr. Shams' personal interests include cooking, yoga, travel and spending time with family and friends.

Professional Affiliations

Testimonials from Dr. Shams' Patients

February 2026

Update: we now have visits at the Mt. Vernon, Sandy Springs location. Jessica is amazing, as is Sarah, and all staff... so very kind and helpful! Dr. Shams is the best! I highly recommend this practice - they are all so very kind to my 95 yr old client. Thank you all for your help in caring for her. Dr. Shams takes her time to explain and makes the complete process as easy as possible for my 93 year old client. Dr. Shams' scheduler is amazing. She takes pride in helping ...she actually cares !!!

January 2026

Dr. Shams is a star on many accounts. The best way I can explain our relationship is that she is like the sister I never had. Our conversations are very frank, built with mutual trust over 30 years of being a patient. She is very knowledgeable and relatable. I always look forward to my appointments because they are always positive and I feel like I have some control over my treatment.

January 2026

Dr. Shams is professional, knowledgeable, and has good bedside manner. She is tagged with an incredible team that is thorough and punctual. I appreciated the time she took to review my charts from my hospital stay, info received from her PA, and answered all of my questions. I visited her Sandy Springs office which was easy to find and had a minimal wait to be seen (which is a huge plus for me). Front office staff is very courteous!

December 2025

The staff is always very friendly, kind and efficient. I never have to wait more than a few minutes to be taken back for bloodwork, etc.

December 2025

Dr. Shams is an excellent Doctor. Took time to hear my problems and concerns.

December 2025

Dr Shams is fabulous; very caring and sensitive.

December 2025

Explains everything in detail and very personal. Dr. Shams is the best.

December 2025

Doctor Shams is a wonderful and And great doctor she takes good care of me and always ask about my family. She she's my favorite doctor.

December 2025

Dr. Shams is always caring and thorough in my son's examination and asks me if we have any concerns. I feel that my son is being treated with the utmost care and compassion.

December 2025

Very patient and thorough. Returns calls and messages promptly. Dr.Shams has a compassionate professionalism about her work. I would HIGHLY recommend her. Great doctor.

December 2025

Dr Shams has been caring for my 93 year old mother for the past 4 years. She is an outstanding doctor with a great bedside manner. I would highly recommend her and her staff to take care of you or your loved ones.

December 2025

Staff excellent, nurse excellent, as always, Dr Shams easy to follow, thorough.

November 2025

As a new patient, I appreciated Dr. Shams and her PA really being thorough in getting to know my health needs and concerns.

November 2025

Dr. Shams is very professional, kind, knowledgeable, thorough and super caring! I feel truly fortunate to have her as my physician. Her staff is so helpful too.

November 2025

Everyone is friendly and efficient. Dr. Shams is nice and caring.

View Testimonials About PCI

Office Locations

Samantha Shams, MD sees patients at the following PCI offices.

The Atlanta office of Piedmont Cancer Institute | Atlanta Oncologists

Atlanta

1800 Howell Mill Rd, Suite 800, Atlanta, GA 30318

404-350-9853

Map & Directions

The Sandy Springs office of Piedmont Cancer Institute | Atlanta Oncologists

Sandy Springs

755 Mount Vernon Hwy NE, Suite 320, Atlanta, GA 30328

404-350-8711

Map & Directions

Seven Atlanta Area Locations

Providing the highest quality cancer treatment services close to home.

WebMD Preferred Provider Castle Connolly Top Physician Practices GASCO Lifetime Group Member Georgia Trend Top Doctors Atlanta Magazine Top Doctors 2024 Atlanta Magazine Top Doctors 2023 Best of Perimeter 2023 Best of North Atlanta 2025 Best of North Atlanta 2024 Atlanta's Best 2023 Kev's Best